CovidSeniorV1, Main, Exploration, bibRecord, 000616

Electrocardiographic findings of methanol toxicity: a cross-sectional study of 356 cases in Iran.

Identifieur interne : 000616 ( Main/Exploration ); précédent : 000615; suivant : 000617

Electrocardiographic findings of methanol toxicity: a cross-sectional study of 356 cases in Iran.

Auteurs : Mohammad Hossein Nikoo [Iran] ; Alireza Arjangzadeh [Iran] ; Maryam Pakfetrat [Iran] ; Shahrokh Sadeghi Boogar [Iran] ; Vahid Mohammadkarimi [Iran] ; Vahid Reza Ostovan [Iran] ; Zohre Khodamoradi [Iran] ; Jamshid Roozbeh [Iran] ; Mohammadreza Khalili [Iran] ; Farnaz Kamali Haghighi Shirazi [Iran] ; Paryia Kouhi [Iran] ; Seyed Taghi Heydari [Iran]

Source :

BMC cardiovascular disorders [ 1471-2261 ] ; 2020.

RBID : pubmed:32928149

Descripteurs français

English descriptors

Abstract

BACKGROUND

Methanol is widely used in industry; however, methanol poisoning is not common. In this regard, a number of outbreaks have been recently reported due to inappropriate processing of alcoholic beverages. Shiraz, a city located in the southern part of Iran, faced one of such outbreaks in 2020 during COVID-19 pandemic. There is no sufficient literature on the electrocardiographic findings in methanol toxicity. This study aimed to address this gap in the literature.

METHOD

A total of 356 cases with methanol toxicity referred to Shiraz University of Medical Science Tertiary Hospitals (Faghihi and Namazi) in March and April, 2020. The clinical findings of blindness and impaired level of consciousness, lab data such as arterial blood gas, electrolytes, and creatinine, and the most common findings from ECGs were collected.

RESULTS

The most common ECG findings were J point elevation (68.8%), presence of U wave (59.2%), QTc prolongation (53.2% in males and 28.6% in females), and fragmented QRS (33.7%). An outstanding finding in this study was the presence of myocardial infarction in 5.3% of the cases. This finding, to the best of our knowledge, has only been reported in a few case reports. Brugada pattern (8.1%) and Osborn wave (3.7%) were the other interesting findings. In multivariate analysis, when confounding factors were adjusted, myocardial infarction, atrioventricular conduction disturbances, sinus tachycardia, and the prolonged QTC > 500 msecond were four independent factors correlated with methanol toxicity severity measured with arterial blood PH on arterial blood gas measurements, with odds ratios of 12.82, 4.46, 2.32 and 3.15 (P < 0.05 for all), respectively.

CONCLUSION

Electrocardiographic variations during methanol intoxication are remarkable and well-correlated with poisoning severity. Myocardial infarction was an egregious and yet a common concerning finding in this sample, which need to be ruled out in methanol toxicity.

DOI: 10.1186/s12872-020-01691-y
PubMed: 32928149
PubMed Central: PMC7488223

Affiliations:

Iran

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<author><name sortKey="Nikoo, Mohammad Hossein" sort="Nikoo, Mohammad Hossein" uniqKey="Nikoo M" first="Mohammad Hossein" last="Nikoo">Mohammad Hossein Nikoo</name>
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<author><name sortKey="Khodamoradi, Zohre" sort="Khodamoradi, Zohre" uniqKey="Khodamoradi Z" first="Zohre" last="Khodamoradi">Zohre Khodamoradi</name>
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<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
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<author><name sortKey="Roozbeh, Jamshid" sort="Roozbeh, Jamshid" uniqKey="Roozbeh J" first="Jamshid" last="Roozbeh">Jamshid Roozbeh</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Internal Medicine, Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
<wicri:noRegion>Shiraz</wicri:noRegion>
</affiliation>
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<author><name sortKey="Khalili, Mohammadreza" sort="Khalili, Mohammadreza" uniqKey="Khalili M" first="Mohammadreza" last="Khalili">Mohammadreza Khalili</name>
<affiliation wicri:level="1"><nlm:affiliation>Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
<wicri:noRegion>Shiraz</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Poostchi Eye Research Centre, Ophthalmology Department, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Poostchi Eye Research Centre, Ophthalmology Department, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
<wicri:noRegion>Shiraz</wicri:noRegion>
</affiliation>
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<author><name sortKey="Shirazi, Farnaz Kamali Haghighi" sort="Shirazi, Farnaz Kamali Haghighi" uniqKey="Shirazi F" first="Farnaz Kamali Haghighi" last="Shirazi">Farnaz Kamali Haghighi Shirazi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
<wicri:noRegion>Shiraz</wicri:noRegion>
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<author><name sortKey="Kouhi, Paryia" sort="Kouhi, Paryia" uniqKey="Kouhi P" first="Paryia" last="Kouhi">Paryia Kouhi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.</nlm:affiliation>
<country xml:lang="fr">Iran</country>
<wicri:regionArea>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz</wicri:regionArea>
<wicri:noRegion>Shiraz</wicri:noRegion>
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<author><name sortKey="Heydari, Seyed Taghi" sort="Heydari, Seyed Taghi" uniqKey="Heydari S" first="Seyed Taghi" last="Heydari">Seyed Taghi Heydari</name>
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<country xml:lang="fr">Iran</country>
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<series><title level="j">BMC cardiovascular disorders</title>
<idno type="eISSN">1471-2261</idno>
<imprint><date when="2020" type="published">2020</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term>
<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Alcoholic Beverages (MeSH)</term>
<term>Atrioventricular Block (blood)</term>
<term>Atrioventricular Block (chemically induced)</term>
<term>Atrioventricular Block (physiopathology)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Blindness (blood)</term>
<term>Blindness (chemically induced)</term>
<term>Blindness (physiopathology)</term>
<term>Blood Gas Analysis (MeSH)</term>
<term>Brugada Syndrome (blood)</term>
<term>Brugada Syndrome (chemically induced)</term>
<term>Brugada Syndrome (physiopathology)</term>
<term>Consciousness Disorders (blood)</term>
<term>Consciousness Disorders (chemically induced)</term>
<term>Consciousness Disorders (physiopathology)</term>
<term>Coronavirus Infections (MeSH)</term>
<term>Electrocardiography (MeSH)</term>
<term>Female (MeSH)</term>
<term>Food Contamination (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Hydrogen-Ion Concentration (MeSH)</term>
<term>Iran (MeSH)</term>
<term>Long QT Syndrome (blood)</term>
<term>Long QT Syndrome (chemically induced)</term>
<term>Long QT Syndrome (physiopathology)</term>
<term>Male (MeSH)</term>
<term>Methanol (poisoning)</term>
<term>Middle Aged (MeSH)</term>
<term>Multivariate Analysis (MeSH)</term>
<term>Myocardial Infarction (blood)</term>
<term>Myocardial Infarction (chemically induced)</term>
<term>Myocardial Infarction (physiopathology)</term>
<term>Pandemics (MeSH)</term>
<term>Pneumonia, Viral (MeSH)</term>
<term>Poisoning (blood)</term>
<term>Poisoning (physiopathology)</term>
<term>Sex Factors (MeSH)</term>
<term>Solvents (poisoning)</term>
<term>Tachycardia, Sinus (blood)</term>
<term>Tachycardia, Sinus (chemically induced)</term>
<term>Tachycardia, Sinus (physiopathology)</term>
<term>Young Adult (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term>
<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Analyse multifactorielle (MeSH)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Bloc atrioventriculaire (induit chimiquement)</term>
<term>Bloc atrioventriculaire (physiopathologie)</term>
<term>Bloc atrioventriculaire (sang)</term>
<term>Boissons alcooliques (MeSH)</term>
<term>Concentration en ions d'hydrogène (MeSH)</term>
<term>Contamination des aliments (MeSH)</term>
<term>Cécité (induit chimiquement)</term>
<term>Cécité (physiopathologie)</term>
<term>Cécité (sang)</term>
<term>Facteurs sexuels (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Gazométrie sanguine (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Infarctus du myocarde (induit chimiquement)</term>
<term>Infarctus du myocarde (physiopathologie)</term>
<term>Infarctus du myocarde (sang)</term>
<term>Infections à coronavirus (MeSH)</term>
<term>Intoxication (physiopathologie)</term>
<term>Intoxication (sang)</term>
<term>Iran (MeSH)</term>
<term>Jeune adulte (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Méthanol (intoxication)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (MeSH)</term>
<term>Solvants (intoxication)</term>
<term>Sujet âgé (MeSH)</term>
<term>Syndrome de Brugada (induit chimiquement)</term>
<term>Syndrome de Brugada (physiopathologie)</term>
<term>Syndrome de Brugada (sang)</term>
<term>Syndrome du QT long (induit chimiquement)</term>
<term>Syndrome du QT long (physiopathologie)</term>
<term>Syndrome du QT long (sang)</term>
<term>Tachycardie sinusale (induit chimiquement)</term>
<term>Tachycardie sinusale (physiopathologie)</term>
<term>Tachycardie sinusale (sang)</term>
<term>Troubles de la conscience (induit chimiquement)</term>
<term>Troubles de la conscience (physiopathologie)</term>
<term>Troubles de la conscience (sang)</term>
<term>Électrocardiographie (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="poisoning" xml:lang="en"><term>Methanol</term>
<term>Solvents</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Iran</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Atrioventricular Block</term>
<term>Blindness</term>
<term>Brugada Syndrome</term>
<term>Consciousness Disorders</term>
<term>Long QT Syndrome</term>
<term>Myocardial Infarction</term>
<term>Poisoning</term>
<term>Tachycardia, Sinus</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Atrioventricular Block</term>
<term>Blindness</term>
<term>Brugada Syndrome</term>
<term>Consciousness Disorders</term>
<term>Long QT Syndrome</term>
<term>Myocardial Infarction</term>
<term>Tachycardia, Sinus</term>
</keywords>
<keywords scheme="MESH" qualifier="induit chimiquement" xml:lang="fr"><term>Bloc atrioventriculaire</term>
<term>Cécité</term>
<term>Infarctus du myocarde</term>
<term>Syndrome de Brugada</term>
<term>Syndrome du QT long</term>
<term>Tachycardie sinusale</term>
<term>Troubles de la conscience</term>
</keywords>
<keywords scheme="MESH" qualifier="intoxication" xml:lang="fr"><term>Méthanol</term>
<term>Solvants</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Bloc atrioventriculaire</term>
<term>Cécité</term>
<term>Infarctus du myocarde</term>
<term>Intoxication</term>
<term>Syndrome de Brugada</term>
<term>Syndrome du QT long</term>
<term>Tachycardie sinusale</term>
<term>Troubles de la conscience</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Atrioventricular Block</term>
<term>Blindness</term>
<term>Brugada Syndrome</term>
<term>Consciousness Disorders</term>
<term>Long QT Syndrome</term>
<term>Myocardial Infarction</term>
<term>Poisoning</term>
<term>Tachycardia, Sinus</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Bloc atrioventriculaire</term>
<term>Cécité</term>
<term>Infarctus du myocarde</term>
<term>Intoxication</term>
<term>Syndrome de Brugada</term>
<term>Syndrome du QT long</term>
<term>Tachycardie sinusale</term>
<term>Troubles de la conscience</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Alcoholic Beverages</term>
<term>Betacoronavirus</term>
<term>Blood Gas Analysis</term>
<term>Coronavirus Infections</term>
<term>Electrocardiography</term>
<term>Female</term>
<term>Food Contamination</term>
<term>Humans</term>
<term>Hydrogen-Ion Concentration</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multivariate Analysis</term>
<term>Pandemics</term>
<term>Pneumonia, Viral</term>
<term>Sex Factors</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analyse multifactorielle</term>
<term>Betacoronavirus</term>
<term>Boissons alcooliques</term>
<term>Concentration en ions d'hydrogène</term>
<term>Contamination des aliments</term>
<term>Facteurs sexuels</term>
<term>Femelle</term>
<term>Gazométrie sanguine</term>
<term>Humains</term>
<term>Infections à coronavirus</term>
<term>Iran</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Pneumopathie virale</term>
<term>Sujet âgé</term>
<term>Électrocardiographie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Methanol is widely used in industry; however, methanol poisoning is not common. In this regard, a number of outbreaks have been recently reported due to inappropriate processing of alcoholic beverages. Shiraz, a city located in the southern part of Iran, faced one of such outbreaks in 2020 during COVID-19 pandemic. There is no sufficient literature on the electrocardiographic findings in methanol toxicity. This study aimed to address this gap in the literature.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHOD</b>
</p>
<p>A total of 356 cases with methanol toxicity referred to Shiraz University of Medical Science Tertiary Hospitals (Faghihi and Namazi) in March and April, 2020. The clinical findings of blindness and impaired level of consciousness, lab data such as arterial blood gas, electrolytes, and creatinine, and the most common findings from ECGs were collected.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>The most common ECG findings were J point elevation (68.8%), presence of U wave (59.2%), QTc prolongation (53.2% in males and 28.6% in females), and fragmented QRS (33.7%). An outstanding finding in this study was the presence of myocardial infarction in 5.3% of the cases. This finding, to the best of our knowledge, has only been reported in a few case reports. Brugada pattern (8.1%) and Osborn wave (3.7%) were the other interesting findings. In multivariate analysis, when confounding factors were adjusted, myocardial infarction, atrioventricular conduction disturbances, sinus tachycardia, and the prolonged QTC > 500 msecond were four independent factors correlated with methanol toxicity severity measured with arterial blood PH on arterial blood gas measurements, with odds ratios of 12.82, 4.46, 2.32 and 3.15 (P < 0.05 for all), respectively.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>Electrocardiographic variations during methanol intoxication are remarkable and well-correlated with poisoning severity. Myocardial infarction was an egregious and yet a common concerning finding in this sample, which need to be ruled out in methanol toxicity.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32928149</PMID>
<DateCompleted><Year>2020</Year>
<Month>09</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>10</Month>
<Day>01</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-2261</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>20</Volume>
<Issue>1</Issue>
<PubDate><Year>2020</Year>
<Month>09</Month>
<Day>14</Day>
</PubDate>
</JournalIssue>
<Title>BMC cardiovascular disorders</Title>
<ISOAbbreviation>BMC Cardiovasc Disord</ISOAbbreviation>
</Journal>
<ArticleTitle>Electrocardiographic findings of methanol toxicity: a cross-sectional study of 356 cases in Iran.</ArticleTitle>
<Pagination><MedlinePgn>415</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1186/s12872-020-01691-y</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Methanol is widely used in industry; however, methanol poisoning is not common. In this regard, a number of outbreaks have been recently reported due to inappropriate processing of alcoholic beverages. Shiraz, a city located in the southern part of Iran, faced one of such outbreaks in 2020 during COVID-19 pandemic. There is no sufficient literature on the electrocardiographic findings in methanol toxicity. This study aimed to address this gap in the literature.</AbstractText>
<AbstractText Label="METHOD">A total of 356 cases with methanol toxicity referred to Shiraz University of Medical Science Tertiary Hospitals (Faghihi and Namazi) in March and April, 2020. The clinical findings of blindness and impaired level of consciousness, lab data such as arterial blood gas, electrolytes, and creatinine, and the most common findings from ECGs were collected.</AbstractText>
<AbstractText Label="RESULTS">The most common ECG findings were J point elevation (68.8%), presence of U wave (59.2%), QTc prolongation (53.2% in males and 28.6% in females), and fragmented QRS (33.7%). An outstanding finding in this study was the presence of myocardial infarction in 5.3% of the cases. This finding, to the best of our knowledge, has only been reported in a few case reports. Brugada pattern (8.1%) and Osborn wave (3.7%) were the other interesting findings. In multivariate analysis, when confounding factors were adjusted, myocardial infarction, atrioventricular conduction disturbances, sinus tachycardia, and the prolonged QTC > 500 msecond were four independent factors correlated with methanol toxicity severity measured with arterial blood PH on arterial blood gas measurements, with odds ratios of 12.82, 4.46, 2.32 and 3.15 (P < 0.05 for all), respectively.</AbstractText>
<AbstractText Label="CONCLUSION">Electrocardiographic variations during methanol intoxication are remarkable and well-correlated with poisoning severity. Myocardial infarction was an egregious and yet a common concerning finding in this sample, which need to be ruled out in methanol toxicity.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Nikoo</LastName>
<ForeName>Mohammad Hossein</ForeName>
<Initials>MH</Initials>
<AffiliationInfo><Affiliation>Non-communicable Disease Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Arjangzadeh</LastName>
<ForeName>Alireza</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Cardiology Department, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pakfetrat</LastName>
<ForeName>Maryam</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Boogar</LastName>
<ForeName>Shahrokh Sadeghi</ForeName>
<Initials>SS</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mohammadkarimi</LastName>
<ForeName>Vahid</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ostovan</LastName>
<ForeName>Vahid Reza</ForeName>
<Initials>VR</Initials>
<AffiliationInfo><Affiliation>Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Poostchi Eye Research Centre, Ophthalmology Department, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Khodamoradi</LastName>
<ForeName>Zohre</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Roozbeh</LastName>
<ForeName>Jamshid</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, Shiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Khalili</LastName>
<ForeName>Mohammadreza</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Poostchi Eye Research Centre, Ophthalmology Department, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Shirazi</LastName>
<ForeName>Farnaz Kamali Haghighi</ForeName>
<Initials>FKH</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kouhi</LastName>
<ForeName>Paryia</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine, School Of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Heydari</LastName>
<ForeName>Seyed Taghi</ForeName>
<Initials>ST</Initials>
<Identifier Source="ORCID">0000-0001-7711-1137</Identifier>
<AffiliationInfo><Affiliation>Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Building No.2.8th Floor School of Medicine Zand Avenue, P.O.Box:71345-1877, Shiraz, Iran. heydari.st@gmail.com.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>98-01-01-22074</GrantID>
<Agency>Vice-Chancellor for Research, Shiraz University of Medical Sciences</Agency>
<Country>International</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>09</Month>
<Day>14</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>BMC Cardiovasc Disord</MedlineTA>
<NlmUniqueID>100968539</NlmUniqueID>
<ISSNLinking>1471-2261</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D012997">Solvents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>Y4S76JWI15</RegistryNumber>
<NameOfSubstance UI="D000432">Methanol</NameOfSubstance>
</Chemical>
</ChemicalList>
<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
<SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName>
</SupplMeshList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000434" MajorTopicYN="N">Alcoholic Beverages</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D054537" MajorTopicYN="N">Atrioventricular Block</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001766" MajorTopicYN="N">Blindness</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001784" MajorTopicYN="N">Blood Gas Analysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053840" MajorTopicYN="N">Brugada Syndrome</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000139" MajorTopicYN="N">chemically induced</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003244" MajorTopicYN="N">Consciousness Disorders</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004562" MajorTopicYN="N">Electrocardiography</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005506" MajorTopicYN="N">Food Contamination</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006863" MajorTopicYN="N">Hydrogen-Ion Concentration</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007492" MajorTopicYN="N" Type="Geographic">Iran</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008133" MajorTopicYN="N">Long QT Syndrome</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000432" MajorTopicYN="N">Methanol</DescriptorName>
<QualifierName UI="Q000506" MajorTopicYN="Y">poisoning</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015999" MajorTopicYN="N">Multivariate Analysis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009203" MajorTopicYN="N">Myocardial Infarction</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011041" MajorTopicYN="N">Poisoning</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012737" MajorTopicYN="N">Sex Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012997" MajorTopicYN="N">Solvents</DescriptorName>
<QualifierName UI="Q000506" MajorTopicYN="Y">poisoning</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013616" MajorTopicYN="N">Tachycardia, Sinus</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">ECG</Keyword>
<Keyword MajorTopicYN="Y">Iran</Keyword>
<Keyword MajorTopicYN="Y">Methanol toxicity</Keyword>
<Keyword MajorTopicYN="Y">Myocardial infarction</Keyword>
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<Month>06</Month>
<Day>09</Day>
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<Month>08</Month>
<Day>27</Day>
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</PubmedData>
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<affiliations><list><country><li>Iran</li>
</country>
</list>
<tree><country name="Iran"><noRegion><name sortKey="Nikoo, Mohammad Hossein" sort="Nikoo, Mohammad Hossein" uniqKey="Nikoo M" first="Mohammad Hossein" last="Nikoo">Mohammad Hossein Nikoo</name>
</noRegion>
<name sortKey="Arjangzadeh, Alireza" sort="Arjangzadeh, Alireza" uniqKey="Arjangzadeh A" first="Alireza" last="Arjangzadeh">Alireza Arjangzadeh</name>
<name sortKey="Boogar, Shahrokh Sadeghi" sort="Boogar, Shahrokh Sadeghi" uniqKey="Boogar S" first="Shahrokh Sadeghi" last="Boogar">Shahrokh Sadeghi Boogar</name>
<name sortKey="Heydari, Seyed Taghi" sort="Heydari, Seyed Taghi" uniqKey="Heydari S" first="Seyed Taghi" last="Heydari">Seyed Taghi Heydari</name>
<name sortKey="Khalili, Mohammadreza" sort="Khalili, Mohammadreza" uniqKey="Khalili M" first="Mohammadreza" last="Khalili">Mohammadreza Khalili</name>
<name sortKey="Khalili, Mohammadreza" sort="Khalili, Mohammadreza" uniqKey="Khalili M" first="Mohammadreza" last="Khalili">Mohammadreza Khalili</name>
<name sortKey="Khodamoradi, Zohre" sort="Khodamoradi, Zohre" uniqKey="Khodamoradi Z" first="Zohre" last="Khodamoradi">Zohre Khodamoradi</name>
<name sortKey="Kouhi, Paryia" sort="Kouhi, Paryia" uniqKey="Kouhi P" first="Paryia" last="Kouhi">Paryia Kouhi</name>
<name sortKey="Mohammadkarimi, Vahid" sort="Mohammadkarimi, Vahid" uniqKey="Mohammadkarimi V" first="Vahid" last="Mohammadkarimi">Vahid Mohammadkarimi</name>
<name sortKey="Ostovan, Vahid Reza" sort="Ostovan, Vahid Reza" uniqKey="Ostovan V" first="Vahid Reza" last="Ostovan">Vahid Reza Ostovan</name>
<name sortKey="Ostovan, Vahid Reza" sort="Ostovan, Vahid Reza" uniqKey="Ostovan V" first="Vahid Reza" last="Ostovan">Vahid Reza Ostovan</name>
<name sortKey="Pakfetrat, Maryam" sort="Pakfetrat, Maryam" uniqKey="Pakfetrat M" first="Maryam" last="Pakfetrat">Maryam Pakfetrat</name>
<name sortKey="Roozbeh, Jamshid" sort="Roozbeh, Jamshid" uniqKey="Roozbeh J" first="Jamshid" last="Roozbeh">Jamshid Roozbeh</name>
<name sortKey="Shirazi, Farnaz Kamali Haghighi" sort="Shirazi, Farnaz Kamali Haghighi" uniqKey="Shirazi F" first="Farnaz Kamali Haghighi" last="Shirazi">Farnaz Kamali Haghighi Shirazi</name>
</country>
</tree>
</affiliations>
</record>

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Electrocardiographic findings of methanol toxicity: a cross-sectional study of 356 cases in Iran.

Electrocardiographic findings of methanol toxicity: a cross-sectional study of 356 cases in Iran.

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